News

FedBatchDesigner

16.05.2025 Tools

© Andrea C. Graf, Julian Libiseller-Egger, Mathias Gotsmy, and Jürgen Zanghellini

A user-friendly dashboard for modeling and optimizing growth-arrested fed-batch processes, enabling exploration of the design space of fed-batch fermentations with a growth-arrested second stage.

Minimal cut sets in metabolic networks: from conceptual foundations to applications in metabolic engineering and biomedicine

23.04.2025 Publications

© Steffen Klamt, Jürgen Zanghellini and Axel von Kamp

Steffen Klamt, Jürgen Zanghellini, and Axel von Kamp

Optimizing VLP production in gene therapy: Opportunities and challenges for in silico modeling

02.05.2023 Publications

© BioRender by Leopold Zehetner, Diana Széliová, Barbara Kraus, Michael Graninger, Jürgen Zanghellini, and Juan A. Hernandez Bort

Leopold Zehetner, Diana Széliová, Barbara Kraus, Michael Graninger, Jürgen Zanghellini, Juan A. Hernandez Bort

ecmtool: fast and memory-efficient enumeration of ECMs

03.03.2023 Tools

© Bianca Buchner, Tom J. Clement, Daan H. de Groot, and Jürgen Zanghellini

Calculate Elementary Conversion Modes (ECMs) from metabolic networks and uncover organisms’ metabolic blueprints with ecmtool. Explore metabolic capabilities.

Finger sweat analysis enables short interval metabolic biomonitoring

13.10.2021 Tools

© Panel a was modified from Servier Medical Art, licensed under a Creative Common Attribution 3.0 Generic License (http://smart.servier.com/) and BioRender (https://biorender.com/). Tf Tracefinder Software, Cd Compound Discoverer Software (both Thermo Fisher Scientific).

Combined with mathematical modelling, sweat metabotyping opens new opportunities for precision medicine and personalized metabolic phenotyping.

PeakBot: machine-learning-based chromatographic peak picking

28.07.2021 Tools

© Christoph Büschl

PeakBot uses machine learning to detect chromatographic peaks in LC-HRMS profile-mode data and provides a high-performance solution for automated peak picking.