Biochemical Network Analysis

Biochemical Network Analysis: Zanghellini Lab
Genuinely curious.

Biochemical Network Analysis: Zanghellini Lab
EVN

Reconstructing life

How do the many reactions inside a cell work together to create and sustain life? We use mathematical modeling and systems biology to understand the structure, dynamics, regulation, and control of metabolic networks.

We develop computational methods to uncover how the structure of metabolic networks shapes cellular function. By turning biological knowledge into quantitative models, we aim not only to predict how cells respond to changes but also to put this knowledge to use. For example, we use our models to design microbes that produce valuable chemicals or biopharmaceuticals more efficiently. Together with experimental partners, we test our predictions and designs in real biological systems.

Ultimately, we want to understand cells well enough to reconstruct their behavior on the computer.

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