ltcs-calculator: largest thermodynamically consistent sets of elementary flux modes

Given a set of elementary flux modes (EFMs), ltcs-calculator calculates the largest thermodynamically consistent sets (LTCSs) of EFMs. An LTCS contains the maximum number of EFMs that can be combined to form a thermodynamically feasible flux distribution. ltcs-calculator is a collection of (command-line) software tools written in C and Perl.

ltcs-calculator is freely available under either the 2-Clause BSD License at GitHub.

References

• Matthias P. Gerstl, Christian Jungreuthmayer, Stefan Müller, and Jürgen Zanghellini. Which sets of elementary flux modes form thermodynamically feasible flux distributions? The FEBS Journal 283:1782 (2016). doi:10.1111/febs.13702